Tag Archives: reduction

It Is Always Wrong to Eat a Baby

(unless the Lord commands it)

This is the house that Jack built.

This is the malt that lay in the house that Jack built.

This is the rat that ate the malt

That lay in the house that Jack built.

This is the cat

That killed the rat that ate the malt

That lay in the house that Jack built.

This is the dog that worried the cat

That killed the rat that ate the malt

That lay in the house that Jack built.

This is the cow with the crumpled horn

That tossed the dog that worried the cat

That killed the rat that ate the malt

That lay in the house that Jack built.

This is the maiden all forlorn

That milked the cow with the crumpled horn

That tossed the dog that worried the cat

That killed the rat that ate the malt

That lay in the house that Jack built.

This is the man all tattered and torn

That kissed the maiden all forlorn

That milked the cow with the crumpled horn

That tossed the dog that worried the cat

That killed the rat that ate the malt

That lay in the house that Jack built

.This is the judge all shaven and shorn

That married the man all tattered and torn

That kissed the maiden all forlorn

That milked the cow with the crumpled horn

That tossed the dog that worried the cat

That killed the rat that ate the malt

That lay in the house that Jack built.

This is the rooster that crowed in the morn

That woke the judge all shaven and shorn

That married the man all tattered and torn

That kissed the maiden all forlorn

That milked the cow with the crumpled horn

That tossed the dog that worried the cat

That killed the rat that ate the malt

That lay in the house that Jack built.

This is the farmer sowing his corn

That kept the rooster that crowed in the morn

That woke the judge all shaven and shorn

That married the man all tattered and torn

That kissed the maiden all forlorn

That milked the cow with the crumpled horn

That tossed the dog that worried the cat

That killed the rat that ate the malt

That lay in the house that Jack built.

This is the horse and the hound and the horn

That belonged to the farmer sowing his corn

That kept the rooster that crowed in the morn

That woke the judge all shaven and shorn

That married the man all tattered and torn

That kissed the maiden all forlorn

That milked the cow with the crumpled horn

That tossed the dog that worried the cat

That killed the rat that ate the malt

That lay in the house that Jack built.

Okay, maybe that’s a little much. How about: “Martin Luther founded Protestantism on October 31, 1517, when he nailed his 95 theses to the church door in Wittenberg.”

This story about Martin Luther is not entirely satisfying though. Even if we build it out like the story of Jack’s house, it would not help us pick Martin Luther out of a lineup. We need a different sort of detail for that task: Empiric details.

There seem to be two basic categories: empiric and historic. The former pertains to the contents of our sensorium – our “facts”. The latter pertains to our activities – a sort of behavioral narrative.

On one sort of historic account, Martin Luther is a particular arrangement of quantum probability fields. However, it is important to keep in mind that one name, be it “Martin Luther” or “specific arrangement of quantum probability fields X”, for the one overall phenomenon is the same as the other. Both have the same contents. It is easy to favor the basic physics account as the “real” account of the phenomenon, because “Martin Luther” is reducible to “a particular arrangement of quantum probability fields”. The reduction in question though, is dependent upon bridge laws, which are definitions upon the two terms. Martin Luther is a biological organism, and a biological organism is describable by the rules of biochemistry which is describable by the rules of organic chemistry, which is describable by the rules of classical physics, which is describable by the rules of quantum physics. In this reduction, the the terms of one description of the same phenomenon are rendered to the terms of a broader, finer grained description. Because subsequent descriptions are finer grained and broader, it is easy to attribute priority to them, but scale is not equivalent to priority, and the bridging definitions, as all definitions, are dependent on both terms in the equation.

But there’s another kind of reduction possible – an empiric reduction. If we look at the carbon atom at the farthest left edge of Martin Luther’s right thumbnail, we find the carbon atom at the farthest left edge of Martin Luther’s right thumbnail and nothing else, because the reductions of the terms in that description, even if taken through the first sort of reduction for each, finally depend on everything else. This second sort of reduction, a mapping sort of reduction, is all that explains the particular carbon atom.

The sort of reduction available for the historical Martin Luther is a flavor of theoretical/historical reduction. He is the man who nailed his theses to the door of the Wittenberg church because he was offended by the sale of indulgences by the church and had come through his studies to see the sale of indulgences as symptomatic of a deeper stagnation and corruption of the institution. The reduction in question is not the same as the explanatory reduction possible with the carbon atom. It does not “map”.

If we were able to magically create a map which captured perfect detail at any scale, and centered the map on the carbon atom, when we turn the dial to its maximum gain, we would expect to see the map merge with our empirical reality so that they were indistinguishable. If we tried to apply the same mapping technology to the historical Martin Luther, we would simply get a thicker and thicker biography of Martin Luther, like the tale of Jack’s house. The historical account of Martin Luther is self referential in a way that the empiric, explanatory account of Martin Luther is not. In unravelling the historical Martin Luther, we get an ever-expanding shell of reports, like an unending set of nesting dolls composed of Martin Luther scandal sheets.

Since Heraclitus, we have known that explanatory reductions are instantaneous. What we have not acknowledged with any frequency, is that historical explanations are timeless. Historical identities are fixed fictions, so that actions can be represented in a useful way. The distortion that fixed identity imparts on historical accounts often proves inconsequential. If I say, from a historical standpoint, that Martin Luther’s hammer hand was driven by offense against indulgences, my analysis is right enough to ground an understanding of Protestantism.

Yet we know that when Martin Luther woke that morning and gathered his hammer, nails, and paper, he probably did not have Protestantism in mind. In fact, he probably went through several psychological transformations on the way to the church which are only vaguely represented and summarized in our historical account.

For the record, Martin Luther nailing his theses to the Wittenberg church door represents the beginning of Protestantism. Reference to fixed identities in that statement (Martin Luther, nails, script on paper) is necessary. It is the price of constructing a narrative. In the case of Protestantism, we encounter little difficulty in maintaining the useful fiction that nails, papers, and Martin Luther are the beginning of Protestantism. We understand that the named phenomena play a role in our narrative.

Though we may place then under glass in reverence, we do not expect to find nascent Protestantism in the nails, papers, or even in Martin Luther. Protestantism is constructed from activities associated with the named phenomena; in fact it is a record of activities associated with those phenomena.

In light of the above, is it always wrong to eat a baby? The statement, “it is always wrong to eat a baby”, is at least consistent. It is a record of psychological activities on the subject. It isn’t the kind of thing that “maps” like the carbon atom in Martin Luther’s fingernail. It is a historic, theoretical statement.

Like all such statements, our moral theories are reducible, via bridge laws, to other theories regarding (in the case of baby eating) genetics, cultural heritage, and the criteria for life itself. And like all such statements, the expansions and contractions from broader, finer grained characterizations to narrower, coarser ones are infinite. So we shouldn’t be surprised if we never “get to the bottom of” moral statements. There simply is no bottom. The best that we can do is recognize them for what they are, a record of activities, and not the activities themselves. We will then feel a little more comfortable with what we already do: prefer different theoretical magnifications in different situations.

Tagged , , ,

Causes, Facts, and Heroin

The lecturer moved his laser-pointer quickly over the loop of neural circuitry. He explained the role of Mu receptors in activating the circuit, which sent a signal round and round and came out as the behavior pattern we call addiction. It was all very neat.

It was so neat the he could have simplified his diagram by replacing the pretty brain graphic with a switch. Off would be synonymous with no addictive behavior. On would equal addictive behavior. If you took the theory, “Addiction = Brain Circuitry” at face value, anything that flips the switch would cause addiction. Yet we know that that situation does not obtain. Heroin flips the switch, but not everyone who takes heroin manifests addictive behavior.

For the advocate of “Addiction = Brain Circuitry”, there are two ways out of this dilemma. First, he can posit a multiplicity of switches. In other words, he can claim that there is an intervening network of necessary, but not sufficient, switches on either side of the Big Switch, mediating the input and output of the addiction circuit. But then in principle, all those switches could also be replaced with a single switch, and you are right back where you started. No limited set of if/then statements will be completely determinative.

The second way out of the non-correspondence dilemma is to simply abandon a complete and transparent explanation, in favor of reliable facts. Neurons are necessary to behaviors, and we know that because, if we zap certain neurons, we can reliably alter corresponding behaviors. That doesn’t exactly explain the behavior, but it lets us move on to knowledge of neural circuits and the experiences which correspond with changing the configurations of those circuits.

One might denigrate the second solution as an abandonment of truth-seeking. Perhaps, but that is not so bad, on a proper notion of truth. In solution #2, you get a theory, which is a set of reliable facts. To get to the truth what you need is an explanatory reduction. In other words, all the switches and their positions for a specific moment of behavior, across the cosmic board. Such an array is purely didactic. It refers to no knowledge, for it cannot reliably correspond with anything. You may think you know something about it, but you don’t – not until you begin to formulate a theory regarding it.

Johnnie shoots a dose of heroin because he has inherited a susceptible set of receptors, because he contains the dendritic representations of certain permissive life-lessons, because he lacks certain inhibitory representations, because he lives in a society which has heroin, because he anticipates certain effects from heroin injections. And on, and on, and on…

At the end of such an exposition (if there even is an end) what we have is just a snap-shot which we have pre-labeled, “Johnnie’s Addiction”. To make any sense of it – to know anything at all about it – we must delve in to the insufficient necessities, and be satisfied with their mere reliability. When we give Johnnie a medicine for his Addiction, we should expect that it will, to some extent, extinguish the behavior. We should expect that if we take away his heroin, his behavior will, to some extent, change. And in fact, our theory does correspond with the facts which it predicts, and upon which rests.

Like the addiction lecturer, we all frequently feel dissatisfied with reliability. We would like some non-provisional knowledge. Give us some truth, please. Aspiring to truth gets us nowhere, though. Truth is too hefty. To riff on Gettier’s classic thought experiment, Smith has the truth when he observes that a person with 10 coins in his pocket will get the job, once Smith sees that a person with 10 coins in his pocket gets the job. Yet he has no knowledge thereby. He cannot be (provisionally) right or wrong in such a statement, any more than a snapshot can be right or wrong (though our subsequent interpretations – theories – of the snapshot may be).

If Smith says, at his next interview, that the person with 10 coins in his pocket will get the job, and he takes care to put 10 coins in his own pocket in hopes of getting the job, then he may know something. He is making a knowledge claim regarding his experience with coins and interviews, and his claim may or may not correspond with his theory’s fact-conditions. Reliability is what he will get, and he will be happy with it, or not, as will we all.

Tagged , , , , , , ,

The Problem with Pain

My gaze swung between the man on the exam table and the radiograph displayed on the lightbox. He must have sensed a problem.

“What?” he asked.

What indeed. The film basically showed his shoulder blade broken in two.

“When did this happen?” I inquired. He had already told me once; I just needed to be sure that I’d heard it correctly.

“Yesterday afternoon,” he said, ” right after lunch.”

“And why did you wait until this afternoon to come in?’

“Well, I’m here mostly to get my wife off my back. If it was up to me, I wouldn’t have come in, but she thought it might be serious or something, because I tossed and turned last night.”

“Well,” I told him, “It is not a surgical problem, but it is a bad injury. You got lucky.”

After a moment’s reflection I added, “Didn’t that hurt?”

“Kind of,” he laughed, “But it eased up pretty quick.”

“Do you need any pain medication?” I asked.

“Oh, no,” he demurred, “Tylenol is doing fine for it.”

After a few more pleasantries, the man got up, walked out of my office, got in his car and drove back to work. Watching him wince slightly as he turned out of the parking lot, I couldn’t help but think of the patient before him – a fellow with no history of serious injury, a normal MRI of the lumbar spine, and disabling back pain.

The man with the back pain had wanted pain medication. I’d had to talk him out of it, which was a difficult task in that era. Because it was the era before the opioid crisis, when we were in the midst of a pain crisis, according to the medical authorities. Clinicians were directed to take everyone’s pain level the same way that we took their temperature, and to treat the abnormalities discovered by our measurements.

For those with eyes to see, the notion behind pathologizing pain was misguided, at least. The whole scheme rested on the idea that pain was simply activity in the neuronal substrate. Change the activity pattern, by activating opiate receptors, for example, and you get rid of the pain.

I am not being very charitable in my description, but I am being as charitable as I need to be. There are more nuanced depictions, which leaven the mix with talk of psychological context and so on, but the same suppressed premise lurks beneath them all. It is this: a chain of causal events ‘add up’ to pain, and that is just what pain is. X+Y+Z = Pain. But the necessity of such arithmetic has been in doubt even before Hume laid its troubles out so nicely for us Westerners.

Breaking down a phenomenon gives you its pieces, but does not grant commutativity. Activating opiate receptors does not reshape their owner’s pain experience according to a fixed script. Receptor activity is part of the description of a painful experience, along with psychological context, and personal history. Yet there is no prior necessity – necessity by law, rather than necessity in fact. We did not make the distinction.

Secure in our estimation of the relationship between the neuronal substrate and the pain experience, we went after opiate receptors like we go after splinters. Our efforts did not force anyone’s pain experience into a box, but we gave everyone who we treated a new pain experience. Sometimes it suited them better; sometimes it suited them worse. Many, many times it settled in the center of their psyches and they fell into orbit around it.

Our engagement with the epidemic of untreated pain predictably ended in chaos. Now we need to extricate ourselves, and what do we turn to but the tool already in hand.

Instead of the reduction to type, we have rebuilt our story of pain, revising our reduction on the basis of the same mistake. Receptors pertain to behaviors – in the neuronal substrate, and so in the psychology, and so in the organism – but pain is a byproduct of the behavioral mechanism. It is an epiphenomenon. Chronic experiencers need counselling, to convince them that the pain is ineffectual, and therefore not real, at least not in any serious way.

Unfortunately, I get to participate in this second shot at commutative reduction, too. It will go just as well as the first.

 

Tagged , , , , , , , , , , , ,

Is a Virus Alive?

life, living matter and, as such, matter that shows certain attributes that include responsiveness, growth, metabolism, energy transformation, and reproduction. – Encyclopedia Brittanica

Close enough, and encompassing the generally accepted criteria: responsiveness, reproduction, metabolism and adaptation. My older son asked the question about viruses the other day. I have been looking forward to this question. It means that he is prepared to understand some things about life which are important. It is a tricky question if considered from the wrong viewpoint. A virus displays some of the characteristics which define a living organism. It can respond to stimuli, attaching to the proper cells and injecting its genetic material through the cell membrane when it makes contact. It can replicate. It can adapt to avoid a host immune response. But it does not have the capacity to metabolize. It cannot, in other words, run its own show. It is entirely dependent on its host organism in that respect. Nor is the virus alone on the gray borders of life. Certain families of bacteria lack some essential metabolic processes which would make them autonomous. They must live inside another cell, and depend on their host’s metabolism to survive. Yet, they too can reproduce, adapt, and respond to stimuli in their environment. Because they have a membrane which is active, biologists are prone to give obligate intracellular bacteria, like mycoplasma and Rickettsia, a break. Most biologists are less charitable when it comes to prions. Prions are mis-folded proteins which replicate by somehow inducing their own conformal change in normally folded proteins with which they come in contact. Prions can reproduce, but they cannot metabolize. They cannot adapt much (although they have managed to pass from cows to humans), but they can respond to their environment, albeit in a very limited way. Still, the difference between the prion and the obligate intracellular bacterium would seem to be one of magnitude rather than quality. Differences in their classification reflect a little bit of membrane chauvinism on the part of biologists. The same prejudice is evident in the gray zone at the other end of the complexity scale. By our criteria for life, is a male angler fish alive? The fish can survive for a short period of time independently, but it cannot carry on its own metabolic processes independently for the long-term. It must rely on a female angler fish. It must quickly sniff out a female and attach itself to her, permanently. The male fish spends most of its existence as a tissue of the female angler fish’s body; its brief, free swimming existence is a transitional aberration. Its ability to adapt is extremely limited. Its existence can be mapped on an algorithm only barely more complex than the one which describes a prion’s lifestyle. So what does differentiate the male angler fish from a mycoplasma bacterium, a virus, or even a prion? A few extra membranes make the only difference. Even our own status as living things is at risk if we apply our criteria strictly. We can certainly reproduce, just like the viruses, obligate intracellular bacteria, prions, and angler fish. But it is questionable whether or not we can independently metabolize. We actually rely on hereditary intracellular symbionts for our primary metabolic process. Without these symbionts, our mitochondria, we could live only minutes on the metabolic processes encoded by our own genetic material. So, we can hardly be blamed for fudging our criteria. We certainly want to call ourselves alive. Since it looks and acts alive, we want to call the male angler fish alive. For practical purposes, we also want to call Rickettsia and mycoplasma alive, as well as viruses from time to time. As for the prions, it is often more convenient to view them as sophisticated toxins rather than living things. And that’s the upshot of my son’s question. The issue of whether or not a virus is alive is only confusing if we consider “life” an actual, efficacious thing. But life is just a category. When we look out across the terrible landscape of things, we see phenomena which cluster about each other by dint of their shared heritage. Our account of our cluster is biology, and our criteria for life provide the outline for our biological stories. This is correct viewpoint on the question of life, and what is alive. But this is not the popular viewpoint. The popular viewpoint attempts to preserve life as a thing, as vital essence or emergent property. Unfortunately, the popular viewpoint is not feasible. It leads inexorably back to the original question rephrased, “where is the life in a thing to be found?” In the end, we find that the essence or the emergent property is explained by the operational mechanisms and properties of the thing in question, but it in turn, explains nothing about the thing; it just notes where that particular thing lies on the vast, terrible landscape of things. Despite its glaring inadequacy, the popular viewpoint remains popular because it seems to save us from losing an idea that we don’t feel comfortable losing. But we don’t need to worry, becoming a category doesn’t vitiate life. We have the things which the category marks clustered around us after all, even if it’s only according to our viewpoint. We can’t escape life anymore than we can climb out of our skins. So, the answer to the question? Sure, a virus is alive – as long as you can explain why.

Tagged , , , , , , ,